Baseline function data on placebo and montelukast studies
| Placebo | Montelukast | |||
| B0 | B1 | B0 | B1 | |
| FEV1 % pred | 89±5 | 84±6* | 84±4 | 82±4 |
| Rrs cm H2O·L−1·s−1 | 4.4±0.3 | 4.8±0.4 | 4.5±0.4 | 4.6±0.4 |
| Pa,O2 mmHg | 102±3 | 100±4 | 102±4 | 103±3 |
| Pa,CO2 mmHg | 39±2 | 38±2 | 41±2 | 39±2 |
| PAa,O2 mmHg | 2±1 | 5±2 | 6±4 | 4±2 |
| Log SDQ | 0.50±0.04 | 0.57±0.06 | 0.56±0.07 | 0.56±0.05 |
| Log SDV | 0.51±0.05 | 0.58±0.07 | 0.49±0.05 | 0.55±0.05 |
| DISP R-E* | 3.5±0.5 | 4.7±1.1 | 3.7±0.7 | 4.2±0.7 |
Data are presented as mean±se. B0: Baseline; B1: 3 h after baseline; FEV1 % pred: forced expiratory volume in one second percentage predicted; Rrs: total resistance of respiratory system; Pa,O2: arterial oxygen tension; Pa,CO2: carbon dioxide arterial tension; PAa,O2: alveolar-arterial oxygen tension difference; Log SDQ: dispersion of blood flow distribution (dimensionless); Log SDV: dispersion of alveolar ventilation (dimensionless); DISP R-E*: dispersion of retention minus excretion inert gases corrected for dead space (dimensionless). 1 mmHg = 0.133 kPa. *: p<0.05 compared with B0.