Pulmonary function tests, metabolic data and breathing pattern analysis obtained at study entry (day 0)#
| Value | |
| Pulmonary function | |
| FEV1 L | 0.92±0.06 (41) |
| FVC L | 2.09±0.12 (65) |
| FEV1/FVC % | 44.2±2.0 (63) |
| PEFR L·s−1 | 3.10±0.23 (49) |
| FEF25–75% L·s−1 | 0.31±0.03 (13) |
| IC L | 1.53±0.11 (63) |
| SVC L | 2.40±0.16 (75) |
| TLC L | 6.46±0.30 (119) |
| FRC L | 4.91±0.29 (164) |
| RV L | 4.07±0.26 (197) |
| sRaw cmH2O·L−1·s−1·L−1 | 27.8±2.4 (687) |
| DL,CO/VA, mL·min−1·mmHg·L−1 | 2.89±0.18 (76) |
| Steady-state rest (room air) | |
| Heart rate beats·min−1 | 91±4 |
| Sa,O2 % | 92.3±0.7 |
| V′O2 mL·kg−1·min−1 | 3.4±0.3 |
| V′O2 L·min−1 | 0.23±0.02 |
| V′CO2 L·min−1 | 0.19±0.02 |
| Respiratory exchange ratio | 0.85±0.02 |
| V′E/V′CO2 | 61.9±4.2 |
| VD/VT estimated % | 49±2 |
| V′E L·min−1 | 11.6±0.7 |
| VT L | 0.69±0.05 |
| VT % pred VC | 21±1 |
| f breaths·min−1 | 17.9±1.2 |
| tI/tTOT | 0.38±0.02 |
| PET,CO2 mmHg | 36.5±1.1 |
Data are presented as mean±sem (% predicted). FEV1: forced expiratory volume in one second; FVC: forced vital capacity; PEFR: peak expiratory flow rate; FEF25–75%: forced mid-expiratory flow; IC: inspiratory capacity; SVC: slow vital capacity; TLC: total lung capacity; FRC: functional residual capacity; RV: residual volume; sRaw: specific airway resistance; DL,CO: carbon monoxide diffusing capacity of the lung; VA: alveolar volume; Sa,O2: arterial oxygen saturation; V′O2: oxygen consumption; V′CO2: carbon dioxide production; V′E: minute ventilation; VD: volume of distribution; VT: tidal volume; f: breathing frequency; tI: inspiratory time; tTOT: total breathing cycle; PET,CO2: end-tidal carbon dioxide tension. #: n = 20, except for body plethysmography (n = 19), for single-breath DL,CO (n = 17) and for metabolic measurements (n = 18).