Intervention | Control | OR (95% CI) | |
Parentally reported symptoms at 0–2 yrs | |||
Wheezing at least once | 64 (127/200) | 57 (113/200) | 1.4 (0.83–2.4) |
Wheezing with awakening at least once | 14 (26 /188) | 17 (30/182) | 0.88 (0.45–1.7) |
Recurrent wheezing ≥4 times | 26 (49/189) | 26 (47/184) | 1.1 (0.61–2.0) |
Night-time cough without a cold at least once | 48 (95/197) | 53 (101/190) | 0.78 (0.46–1.3) |
Parentally reported current# symptoms at 2 yrs | |||
Wheezing | 8 (15/187) | 15 (25/171) | 0.73 (0.56–0.96)¶ |
Shortness of breath | 16 (30/187) | 25 (43/171) | 0.76 (0.61–0.96)¶ |
Night-time cough | 44 (57/184) | 56 (72/168) | 0.72 (0.55–0.95)¶ |
GP-recorded morbidity at 0–2 yrs | |||
Wheezing without fever at least once | 34 (72/212) | 40 (80/200) | 0.87 (0.72–1.1) |
Shortness of breath at least once | 27 (57/212) | 31 (62/200) | 0.90 (0.73–1.1) |
Coughing at least once | 68 (144/212) | 70 (139/200) | 0.96 (0.77–1.2) |
Diagnosis asthma | 26 (54/212) | 31 (61/200) | 0.88 (0.72–1.1) |
Diagnosis atopic eczema | 27 (58/212) | 23 (46/200) | 1.1 (0.88–1.4) |
Data are presented as % (n/N), unless otherwise stated. GP: general practitioner; OR: odds ratio; CI: confidence interval. #: at least one diary-reported episode in the last 4 weeks before the 2nd birthday; ¶: significant effects.