Survivors | Nonsurvivors | p-value | |
Subjects n | 34 | 13 | |
Age yrs | 60.1±13.5 | 66.5±12.6 | 0.146 |
Males/females n | 20/14 | 11/2 | 0.321 |
APACHE II score | 19.7±5.4 | 22.5±6.4 | 0.135 |
Pa,O2/FI,O2 mmHg | 211±77 | 142±46 | 0.001 |
Reason for MV n | 0.41 | ||
Post-operative respiratory failure | 5 | 3 | |
AECB | 6 | 2 | |
Sepsis | 3 | 0 | |
Neurological disease or NMD | 1 | 1 | |
CAP# | 3 | 3 | |
Coma | 1 | 0 | |
Cardiac failure | 5 | 0 | |
Trauma | 7 | 2 | |
Other¶ | 3 | 2 | |
Prior infection n | 18 | 11 | 0.046 |
CRP antibiotic response n | <0.001 | ||
Fast response | 10 | 0 | |
Slow response | 20 | 0 | |
Nonresponse | 2 | 7 | |
Biphasic response | 2 | 6 |
Data are presented as n and mean±sd, unless otherwise stated. APACHE: Acute Physiology, Age, and Chronic Health Evaluation; Pa,O2: arterial oxygen tension; FI,O2: inspiratory oxygen fraction; MV: mechanical ventilation; AECB: acute exacerbation of chronic bronchitis; NMD: neuromuscular disease; CAP: community-acquired pneumonia; CRP: C-reactive protein. #: isolates of Pseudomonas aeruginosa (n = 3), Klebsiella spp. (n = 1), methicillin-resistant Staphylococcus aureus (n = 1) and Escherichia coli (n = 1); ¶: cardiopulmonary resuscitation (n = 1), shock (n = 2) and poisoning (n = 2). 1 mmHg = 0.133 kPa.