Young | Older | ||||
Lifelong nonsmokers | Current smokers | Lifelong nonsmokers | Current smokers | ||
Emphysema − | Emphysema + | ||||
Subjects n | 9 | 9 | 7 | 9 | 7 |
Age yrs | 23±1 | 23±1 | 63±3 | 51±2¶ | 49±3¶ |
Cigarettes·day−1 n | 0 | 21±3 | 0 | 27±4 | 33±4 |
Pack-yrs | 0 | 5±1 | 0 | 45±4 | 46±9 |
VC % pred | 100±4 | 96±5 | 122±8 | 112±5 | 100±8 |
FEV1 % pred | 83±4 | 88±4 | 124±8 | 104±4 | 94±8¶ |
FEV1/VC % | 96±1 | 87±2# | 84±2 | 80±2 | 76±3¶ |
DL,CO % pred | NA | NA | NA | 96±5 | 84±7 |
Data are presented as n and mean±se. −: without; +: with; VC: vital capacity; FEV1: forced expiratory volume in one second; DL,CO: carbon monoxide diffusing capacity of the lung; NA: not available. #: p<0.05 versus young lifelong nonsmokers; ¶: p<0.05 versus older lifelong nonsmokers.