Table 2—

Molecular characteristics of human interleukin-17 family of cytokines

SubtypeMr kDaLength AA residuesChromosomal location (GeneID#)Common structural characteristics
A35 1, 2155 1, 22 (3605) 1, 2Cysteine residues 1, 2, 145–149
B41 150180 1455 (55540) 145Disulphide linkages 1, 2, 145–149
C40 145197 14516 (27189) 145Glycoproteins 1, 2, 145–149
D52 146202 14613 (53342) 146Homodimers 1, 2, 145–149
E34 148161 147, 14814 (64806) 148
F44 149153 1496 (112744) 149, 151
  • Mr: relative molecular mass; AA: amino acid; GeneID: gene identifier. #: further gene and protein information in 144.