Table. 3—

3 Effects of bosentan treatment on haemodynamics and blood gas analyses

Patient No.Pra mmHgPpa mmHgCO L·min−1CI L·min−1·m−2Ppcw mmHgPVR dyn·s·cm−5SV mLSv,O2 %Pa mmHgPa,O2 TorrPa,CO2 TorrPAa,O2 Torr
BL1 yrBL1 yrBL1 yrBL1 yrBL1 yrBL1 yrBL1 yrBL1 yrBL1 yrBL1 yrBL1 yrBL1 yr
13055564.86.32.43.173800673707768667976866133342346
25354185.08.12.64.285741128718565699764746332293651
320345494.56.72.03.256717509438751747464747129354035
4141169762.34.01.52.891420851247476748649176766535393036
511453504.75.42.32.5111071459257826464103103655730324752
611249425.16.73.04.0812642322698167699496605833334951
74250353.44.32.32.712108935493546585592104474628316865
83750459.27.85.04.3284173789610774728484605832355048
90443575.65.52.92.847552725666467689192676835323942
10162170502.93.31.51.866177210512730515610379725733383745
11142149503.44.21.92.3581048806473950359079433140395770
Mean±sd9±67±753±948±144.6±1.85.7±1.62.5±1.03.1±0.87±38±3944±519635±32157±2070±2360±963±1191±983±1465±358±1133±334±343±1349±11
p-value0.350.230.020.020.310.0070.0140.400.090.0060.120.04
  • Pra: right atrial pressure; Ppa: mean pulmonary arterial pressure; CO: cardiac output; CI: cardiac index; Ppcw: pulmonary capillary wedge pressure; PVR: pulmonary vascular resistance; SV: stroke volume; Sv,O2: mixed venous oxygen saturation; Pa: mean arterial pressure; Pa,O2: arterial oxygen tension; Pa,CO2: arterial carbon dioxide tension; PAa,O2: alveolar–arterial oxygen tension difference; BL: baseline. 1 Torr = 0.133 kPa.