Table. 1—

1 Clinical and laboratory features at diagnosis of nontuberculous mycobacteria(NTM) lung disease

CaseAge yrsCFTR mutationP. aeruginosa infectionABPASteroid therapy monthsAFBNTMNTM-positive cultures
117ΔF508/W1282X+40+++M. abscessus>5
27W1282X/G542X++48+++M. abscessus>5
333W1282X/N1303K+2#+++M. abscessus>5
48N1303K/1717-1-G->A++24+++M. abscessus>5
511ΔF508/ΔF508++6+++M. simiae>3
618G542X/N1303K++0++M. abscessus>3
  • CFTR: cystic fibrosis transmembrane regulator; P. aeruginosa: Pseudomonas aeruginosa; ABPA: allergic bronchopulmonary aspergillosis; AFB: acid-fast bacilli; −: negative; +: positive; +++: positive NTM culture, with high density on smear; ++: positive NTM culture, with low density on smear; M. abscessus: Mycobacterium abscessus; M. simiae: Mycobacterium simiae. #: steroid therapy for drug allergy during oesophageal carcinoma treatment; : ABPA was diagnosed after NTM infection.