Case | Age yrs | CFTR mutation | P. aeruginosa infection | ABPA | Steroid therapy months | AFB | NTM | NTM-positive cultures |
1 | 17 | ΔF508/W1282X | − | + | 40 | +++ | M. abscessus | >5 |
2 | 7 | W1282X/G542X | + | + | 48 | +++ | M. abscessus | >5 |
3 | 33 | W1282X/N1303K | + | − | 2# | +++ | M. abscessus | >5 |
4 | 8 | N1303K/1717-1-G->A | + | + | 24 | +++ | M. abscessus | >5 |
5 | 11 | ΔF508/ΔF508 | + | + | 6 | +++ | M. simiae | >3 |
6 | 18 | G542X/N1303K | + | +¶ | 0 | ++ | M. abscessus | >3 |
CFTR: cystic fibrosis transmembrane regulator; P. aeruginosa: Pseudomonas aeruginosa; ABPA: allergic bronchopulmonary aspergillosis; AFB: acid-fast bacilli; −: negative; +: positive; +++: positive NTM culture, with high density on smear; ++: positive NTM culture, with low density on smear; M. abscessus: Mycobacterium abscessus; M. simiae: Mycobacterium simiae. #: steroid therapy for drug allergy during oesophageal carcinoma treatment; ¶: ABPA was diagnosed after NTM infection.