Baseline | 2,650 m | p-value | |
FEV1 % pred | 66 (26–107) | 69 (30–115) | <0.001 |
FVC % pred | 85 (51–108) | 88 (47–119) | 0.02 |
Tiffeneau index¶ | 65.7 (34.0–89.0) | 68.0 (44.0–86.0) | 0.001 |
PEF % pred | 72 (24–112) | 88 (42–132) | <0.001 |
MEF25 % pred | 19 (0–75) | 28 (8–76) | <0.001 |
Raw kPa·s−1·L−1 | 0.4 (0.1–1.1) | 0.32 (0.16–1.10) | 0.009 |
ITGV % pred | 117 (63–196) | 132 (70–194) | <0.001 |
TLC % pred | 105 (66–131) | 109 (66–142) | 0.032 |
RV % pred | 152 (79–286) | 188 (68–341) | 0.14 |
Pa,O2 kPa | 9.8 (8.0–13.0) | 7.0 (5.3–10.5) | <0.001 |
Pa,CO2 kPa | 5.1 (4.4–6.0) | 4.7 (3.7–6.0) | <0.001 |
Sa,O2 % | 95 (89–99) | 90 (66–98) | <0.001 |
Pulse rate | 83 (66–110) | 84 (66–118) | 0.059 |
Data are presented as median (range), unless otherwise stated. FEV1: forced expiratory volume in one second; FVC: forced vital capacity; PEF: peak expiratory flow; MEF25: maximal expiratory flow when 25% of the FVC remains to be exhaled; Raw: airway resistance; ITGV: intrathoracic gas volume; TLC: total lung capacity; RV: residual volume; Pa,O2: arterial oxygen tension; Pa,CO2: arterial carbon dioxide tension; Sa,O2: arterial oxygen saturation; % pred: percentage of the predicted value. #: (530 m above sea level); ¶: FEV1/FVC.