Table. 1—

Respiratory parameters at baseline# and after 1 h at an altitude of 2,650 m

Baseline2,650 mp-value
FEV1 % pred66 (26–107)69 (30–115)<0.001
FVC % pred85 (51–108)88 (47–119)0.02
Tiffeneau index65.7 (34.0–89.0)68.0 (44.0–86.0)0.001
PEF % pred72 (24–112)88 (42–132)<0.001
MEF25 % pred19 (0–75)28 (8–76)<0.001
Raw kPa·s−1·L−10.4 (0.1–1.1)0.32 (0.16–1.10)0.009
ITGV % pred117 (63–196)132 (70–194)<0.001
TLC % pred105 (66–131)109 (66–142)0.032
RV % pred152 (79–286)188 (68–341)0.14
Pa,O2 kPa9.8 (8.0–13.0)7.0 (5.3–10.5)<0.001
Pa,CO2 kPa5.1 (4.4–6.0)4.7 (3.7–6.0)<0.001
Sa,O2 %95 (89–99)90 (66–98)<0.001
Pulse rate83 (66–110)84 (66–118)0.059
  • Data are presented as median (range), unless otherwise stated. FEV1: forced expiratory volume in one second; FVC: forced vital capacity; PEF: peak expiratory flow; MEF25: maximal expiratory flow when 25% of the FVC remains to be exhaled; Raw: airway resistance; ITGV: intrathoracic gas volume; TLC: total lung capacity; RV: residual volume; Pa,O2: arterial oxygen tension; Pa,CO2: arterial carbon dioxide tension; Sa,O2: arterial oxygen saturation; % pred: percentage of the predicted value. #: (530 m above sea level); : FEV1/FVC.