Relationship between inoculum size and diagnostic criteria in the rabbit model of pneumococcal pneumonia
| Inoculum size log10 cfu | Diagnostic criterion | Pneumonia | |||||
| Clinical | Radiological | Laboratory | Microbiological | Macroscopic | Histological | ||
| 0# | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 3.267 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
| 3.279 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
| 4.389 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
| 4.505 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
| 4.544 | 0 | 1 | 0 | 1 | 0 | 0 | 1 |
| 4.602 | 1 | 1 | 0 | 1 | 1 | 1 | 1 |
| 4.724 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 5.342 | 1 | 1 | 0 | 1 | 1 | 1 | 1 |
| 5.389 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
| 5.477 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
| 5.505 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
| 5.525 | 1 | 1 | 0 | 1 | 1 | 1 | 1 |
| 5.550 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
| 5.550 | 1 | 1 | 0 | 1 | 1 | 1 | 1 |
| 6.182 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| 6.182 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 6.204 | 1 | 1 | 0 | 1 | 1 | 1 | 1 |
| 6.433 | 1 | 1 | 0 | 1 | 1 | 1 | 1 |
| 6.608 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
| 6.608 | 1 | 1 | 0 | 1 | 1 | 1 | 1 |
| 6.633 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
| 6.633 | 0 | 1 | 1 | 1 | 1 | 1 | 1 |
| 6.796 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
| 7.562 | 1 | 1 | 0 | 1 | 1 | 1 | 1 |
cfu: colony-forming unit; 0: negative result; 1: positive result. #: three control rabbits.