Table. 3—

3 Crude and adjusted geometric mean nitric oxide levels in exhaled air(FE,NO; ppb) for high and low-risk children

High-risk childrenLow-risk children
n#CrudeAdjusted (95% CI)n#CrudeAdjusted (95% CI)
Doctor's diagnosed asthma −2357.87.8(7.4–8.3)1417.97.9(7.4–8.4)
Doctor's diagnosed asthma +1510.2§10.2§(8.3–12.6)310.09.4(5.9–14.8)
Never wheeze1327.97.8(7.3–8.4)898.08.1(7.4–8.8)
Early transient wheeze758.28.2(7.4–9.0)397.97.8(6.9–8.9)
Late/persistent wheeze308.58.6(7.4–10.1)128.48.3(6.6–10.4)
Specific IgE −1137.77.6(7.1–8.3)667.87.8(7.1–8.5)
Specific IgE +378.89.0ƒ(7.9–10.4)1010.5ƒ10.7ƒ(8.4–13.5)
Eosinophilia −987.77.7(7.1–8.4)558.28.3(7.5–9.1)
Eosinophilia +408.38.3(7.3–9.5)228.88.5(7.3–10.0)
Asthma − IgE −1087.67.6(7.0–8.2)647.87.8(7.1–8.5)
Asthma − IgE +348.38.4(7.3–9.7)1010.5##10.7##(8.4–13.5)
Asthma + IgE −59.38.8(6.2–12.6)28.77.6(4.5–12.8)
Asthma + IgE +317.7##19.0##(12.0–30.2)0
  • #: Children using inhaled corticosteroids were excluded from analysis; : geometric mean FE,NO value (95% confidence interval (CI)) (ppb), adjusted for study region and symptoms of cold in the 2 weeks before FE,NO measurement; −: negative; +: positive; §: p<0.05 as compared with geometric mean FE,NO in children without doctor's diagnosed asthma; ƒ: p<0.05 as compared with geometric mean FE,NO in children without specific immunoglobulin (Ig)E; ##: p<0.05 as compared with geometric mean FE,NO in children without asthma and without specific IgE.