Table. 2—

2 Response to hypoxia and to exercise

	Rest			Exercise at PASP_max
	Normoxia	Hypoxia	p-value	Normoxia	Hypoxia	p-value
f_C min⁻¹
HAPE susceptible	64±11	64±11		137±17	117±8	<0.001
Controls	67±8	69±11		141±16	117±15	<0.001
p-value	0.33	0.20		0.48	0.97
S_a,O₂ %
HAPE susceptible	98±1	75±9	<0.001	96±2	69±7	<0.001
Controls	98±1	78±8	<0.001	97±2	72±5	<0.001
p-value	0.45	0.28		0.52	0.16
PASP mmHg
HAPE susceptible	25±5	48±10	<0.001	57±14	69±13	<0.001
Controls	23±5	38±3	<0.001	38±7	49±8	<0.01
p-value	0.42	<0.001		<0.001	<0.001
W W·kg⁻¹
HAPE susceptible				2.4±0.5	1.2±0.3	<0.001
Controls				2.3±0.5	1.1±0.4	<0.001
p-value				0.56	0.33

Data are presented as mean±sd. PASP_max: maximum pulmonary artery systolic pressure; f_C: cardiac frequency; HAPE: high-altitude pulmonary oedema; S_a,O₂: arterial oxygen saturation; PASP: pulmonary artery systolic pressure; W: workload. Significances from normoxic to hypoxic condition and differences between subjects susceptible to HAPE and controls are indicated.