Table 2—

Absolute concentration of bronchoalveolar lavage fluid (BALF) oxidation markers and antioxidants

ControlARDS all patientsPrimary ARDSSecondary ARDS
GSSG µM0.032±0.0160.125±0.024***0.120±0.031**0.140±0.040**
F2-isoprostanes pM26.3±5.277.9±10.2***77.3±12.7**79.8±15.5**
GSH µM1.56±0.201.51±0.341.55±0.441.36±0.28
Ascorbic acid µM0.51±0.052.36±0.60*2.25±0.72*2.73±0.98**
Uric acid µM0.70±0.0411.80±2.22***10.20±1.65***17.16±4.17***
α-Tocopherol nM26.4±3.0977.3±15.1**84.6±18.8**52.1±15.3
Retinol nM4.8±1.032.3±9.5***34.8±12.1***23.8±5.7***
Plasmalogens ng·mL−1367.9±50.3206.5±29.1***191.9±42.3*216.9±40.8*
PUFA µg·mL−12.38±0.286.71±0.95***6.32±1.29*6.99±1.37*
  • Data are presented as mean±sem. The absolute concentrations of oxidised glutathione (GSSG), F2-isoprostanes, reduced glutathione (GSH), vitamins C (ascorbic acid), E (α-tocopherol) and A (retinol), uric acid, plasmalogens, and polyunsaturated fatty acids (PUFA) are given. Acute respiratory distress syndrome (ARDS) patients were further divided into primary and secondary ARDS. *: p<0.05; **: p<0.01; ***: p<0.001 compared with controls