Table 3—

Correlation between computed tomography parameters and aerosol parameters for the whole patient group and for each subgroup

All patients#Usual COPDAAD+
PD15RA-910PD15RA-910PD15RA-910
EAD20-0.67**0.64**-0.220.15-0.80**0.71**
ABD600-0.180.170.00-0.06-0.260.24
  • COPD: chronic obstructive pulmonary disease; AAD: α1-antitrypsin deficiency; PD15: 15th percentile density; RA-910: relative area below -910 Hounsfield units; EAD20: effective airway diameter for a relative volumetric lung depth of 20% of the intrathoracic lung volume at breath hold; ABD600: aerosol bolus dispersion for boluses inhaled into a volumetric lung depth of 600 cm3. #: n = 42; : n = 20; +: n = 22. **: p<0.01.