Lung function before and after exposure in a swine house# in subjects treated with placebo or fluticasone propionate¶
| Subjects n | Pre-exposure VC % pred | Post-exposure ΔVC % | Pre-exposure FEV1 % pred | Post-exposure ΔFEV1 % | |
| Placebo | 8 | 89.1±10.0 | −3.6±2.9** | 95.1±7.3 | −7.8±4.1** |
| Fluticasone propionate | 7 | 97.1±7.9 | −1.9±1.5* | 99.9±12.0 | −4.9±2.6** |
| Between-group p-value | 0.4 | 0.4 |
Data are presented as mean±sd
There was no significant difference between the groups (t-test)
VC: vital capacity
Δ: change
FEV1: forced expiratory volume in one second
#: before medication and 7 h after exposure
¶: for 2 weeks prior to exposure
*: p<0.05
**: p<0.01 versus pre-exposure values