Table 2—

Lung function data in asthmatic subjects

Subject numberAge yrsFEV1 % predFEV1/FVCDecrease in FEV1 % baselineIC postchallenge in laboratoryIC postchallenge at HRCTIC postchallenge HRCT % baselineMethacholine concentration mg·mL−1
1444440.52172.041.05390.25
1528790.76363.373.30891
1626650.77142.403.05952
1728940.723.254
1833680.53273.303.40723.05#
1947530.56162.702.60930.40#
2038770.67342.602.60630.40#
35±369±60.65±0.0424±82.81±0.192.67±0.6975±17
  • Data are presented as n or mean±sem

  • IC postchallenge (% baseline) is mean of the postchallenge IC in the CT suite expressed as a percentage of the prechallenge IC measured in the laboratory challenge

  • FEV1 % pred: forced expiratory volume in one second as a percentage of the predicted values

  • FVC: forced vital capacity

  • IC: inspiratory capacity

  • HRCT: high-resolution computed tomography

  • #: methacholine dose (µmol)

  • : subject was unable to perform technically satisfactory spirometry post CT scan