Table 1—

Lung function data in normal subjects

Subject numberAge yrsFEV1 % predFEV1/FVCDecrease in FEV1 % baselineIC postchallenge in laboratoryIC postchallenge at HRCTIC postchallenge HRCT % baselineMethacholine concentration mg·mL−1
127830.89302.142.20678
233730.82501.821.4562256
331820.78213.052.65798
429940.83662.452.055116
535910.7873.613.541032
625920.81374.003.75884
732980.87203.213.1077256
841790.77134.002.859032
934840.8393.603.5286256
1039880.81193.85UA1072
1126720.72
1222850.85
1334830.83
31±285±20.81±0.0127±63.17±0.252.79±0.2681±520#
  • Data are presented as n or mean±sem

  • IC postchallenge (% baseline) is mean of the postchallenge IC in the CT suite expressed as a percentage of the prechallenge IC measured in the laboratory challenge

  • FEV1 % pred: forced expiratory volume in one second as a percentage of the predicted values

  • FVC: forced vital capacity

  • IC: inspiratory capacity

  • HRCT: high-resolution computed tomography

  • UA: unavailable

  • #: Geometric mean

  • : same IC used for the baseline HRCT