Table 3—

Spearman's correlations (ρ) of changes (Δ) in clinical and inflammatory parameters with Δ in provocative concentration causing a 20% fall in forced expiratory volume in one second (PC20) of methacholine (Mch) or PC20 of adenosine-5'-monophosphate (AMP) during a 1-yr smoking cessation

ΔPC20 MchΔPC20 AMP
ρp-valueρp-value
ΔFEV1 % pred0.0750.800.180.53
ΔFEV1/VC %−0.1060.720.060.85
ΔsGaw 1·kPa−1·s−10.0040.990.0770.79
Sputum 103·mL−1
 Δ Cell concentration−0.320.270.0440.8
 Δ Eosinophils−0.0360.91−0.360.23
 Δ Neutrophils0.180.56−0.0080.98
 Δ Macrophages−0.150.640.0830.79
 Δ Lymphocytes0.340.260.280.36
 Δ Epithelial cells−0.110.71−0.140.65
  • FEV1: forced expiratory volume in one second

  • VC: vital capacity

  • sGaw: airway conductance