Table 2—

Spearman's rank correlations (ρ) of clinical and inflammatory parameters with provocative concentration causing a 20% fall in forced expiratory volume in one second (PC20) of methacholine (Mch) and PC20 of adenosine-5'-monophosphate (AMP)

PC20 MchPC20 AMP
ρp-valueρp-value
Subjects n3029
Age−0.360.052−0.300.12
Sex0.0160.930.0890.65
Pack yrs−0.0970.61−0.190.34
Cigarettes·day−10.260.170.280.14
FEV1 % pred0.750.000.580.001
FEV1/VC %0.820.000.870.00
sGaw 1·kPa−1·s−10.700.000.690.00
Sputum 103·mL−1
 Cell concentration0.0860.650.0800.68
 Eosinophils−0.320.085−0.210.28
 Neutrophils0.0090.96−0.0320.87
 Macrophages0.260.160.230.22
 Lymphocytes−0.0710.71−0.060.75
 Epithelial cells−0.250.18−0.180.36
  • FEV1: forced expiratory volume in one second

  • VC: vital capacity

  • sGaw: airway conductance