Baseline characteristics by exacerbation status: exacerbators versus nonexacerbators
| Number of exacerbations | Frequency of exacerbations | |||||
| None | ≥1 | p-value | <1.65·yr−1 | >1.65·yr−1 | p-value | |
| Subjects n | 93 | 520 | 291 | 286 | ||
| Sex M % | 86 | 73 | 0.009 | 72 | 74 | 0.7 |
| Age yrs | 65±7 | 64±7 | 0.06 | 63±7 | 64±7 | 0.05 |
| Current smokers % | 52 | 48 | 0.6 | 48 | 48 | 0.9 |
| SGRQ total score | 42±17 | 50±17 | <0.0001 | 48±18 | 52±15 | 0.03 |
| FEV1 % pred | 55±15 | 49±15 | 0.001 | 53±15 | 45±13 | <0.0001 |
Data are presented as mean±sd unless otherwise stated
Mean exacerbation rate in patients with exacerbations >0 and <1.65·yr−1 was 0.9·yr−1, and in patients with exacerbations >1.65·yr−1 was 2.8·yr−1
M: male
SGRQ: St Georges Respiratory Questionnaire
FEV1: forced expiratory volume in one second