FEV1 ≤25% pred (without reversibility) and/or |
Resting room air Pa,CO2 >7.3 kPa (55 mmHg) and/or |
Elevated Pa,CO2 with progressive deterioration requiring long-term oxygen therapy |
Elevated pulmonary arterial pressure with progressive deterioration |
FEV1: forced expiratory volume in one second
Pa,CO2: arterial carbon dioxide tension