Oxygen saturation (%) during total sleep time and differences between treatment groups at end of study
| Comparison | Tiotropium-AM | Tiotropium-PM | Tiotropium pooled | Placebo | Difference in % points | p-value | 95% CI |
| Subjects n | 21 | 18 | 39 | 13 | |||
| Tiotropium-AM versus placebo | 89.83 (0.84) | 87.82 (1.05) | 2.01 | 0.141 | −0.69–4.71 | ||
| Tiotropium-PM versus placebo | 90.88 (0.92) | 87.82 | 3.06 | 0.035 | 0.23–5.91 | ||
| Tiotropium pooled versus placebo | 90.31 (0.61) | 87.82 | 2.49 | 0.047 | 0.02–4.93 |
Data are presented as mean (se) unless otherwise stated and are from the patient population with total sleep time of at least 2 h
Means are adjusted for baseline arterial oxygen saturation (Sa,O2) and arterial oxygen tension
Overall mean baseline Sa,O2 during total sleep time=89.58%