Table 3—

Estimates of dose of budesonide (µg·day−1) giving peak effect and effect on mean change in outcome measure

Outcome measureR2 %Fixed-effects modelRandom-effects model
Dose of peak effectMean change (95% CI)Dose of peak effectMean change (95% CI)
FEV1 L3910840.29 (0.19–0.40)10900.30 (0.15–0.45)
Morning PEF L·min−13988158.2 (45–72)97661.8 (35.4–88.1)
Evening PEF L·min−15092636.6 (25–48.2)105040.2 (11.7–68.8)
β‐agonist use puffs·day−152965−2.54 (−0.78–−4.35)1038−2.76 (−6.33–−0.81)
  • CI: confidence interval

  • FEV1: forced expiratory volume in one second

  • PEF: peak expiratory flow