0 infections (or negative for serology section) | ≥1 infection (or positive for serology section) | Adjusted OR* (95% CI) (per episode for infections) | p‐value | Adjusted OR# (95% CI) for association between atopy and number of brothers | p‐value | |||
n | n (%) atopic | n | n (%) atopic | |||||
Serology | ||||||||
Hepatitis A serology | 818 | 303 (37) | 78 | 28 (36) | 0.96 (0.56–1.64) | 0.88 | 0.81 (0.69–0.94) | 0.01 |
Helicobacter serology | 745 | 278 (37) | 151 | 53 (35) | 0.87 (0.57–1.33) | 0.52 | 0.81 (0.70–0.95) | 0.01 |
Infections | ||||||||
All infections | 51 | 20 (39) | 687 | 249 (36) | 1.01 (0.98–1.04) | 0.41 | 0.74 (0.61–0.90) | 0.001 |
All respiratory infections | 167 | 61 (37) | 571 | 208 (36) | 1.03 (0.99–1.07) | 0.13 | 0.74 (0.62–0.90) | 0.001 |
All nonrespiratory infections | 138 | 52 (38) | 600 | 217 (36) | 0.99 (0.94–1.05) | 0.72 | 0.73 (0.61–0.89) | 0.001 |
Lower respiratory infections | 325 | 117 (36) | 413 | 152 (37) | 1.08 (1.01–1.16) | 0.02 | 0.74 (0.61–0.89) | 0.001 |
Upper respiratory infections | 263 | 92 (35) | 475 | 177 (37) | 1.00 (0.94–1.07) | 0.93 | 0.74 (0.61–0.89) | 0.001 |
Ear infections | 497 | 182 (37) | 241 | 87 (36) | 1.00 (0.86–1.17) | 1.00 | 0.74 (0.61–0.89) | 0.001 |
Skin infections | 404 | 148 (37) | 334 | 121 (36) | 1.05 (0.94–1.17) | 0.37 | 0.74 (0.62–0.90) | 0.002 |
Eye infections | 541 | 192 (36) | 197 | 77 (39) | 1.21 (0.96–1.51) | 0.10 | 0.74 (0.62–0.90) | 0.001 |
Urinary tract infections | 669 | 247 (37) | 69 | 22 (32) | 0.95 (0.68–1.33) | 0.76 | 0.74 (0.61–0.89) | 0.001 |
Gastrointestinal infections | 535 | 210 (39) | 203 | 59 (29) | 0.75 (0.59–0.97) | 0.02 | 0.72 (0.60–0.87) | 0.001 |
Other infections | 480 | 184 (38) | 258 | 85 (33) | 0.83 (0.68–1.01) | 0.05 | 0.73 (0.61–0.89) | 0.001 |
OR: odds ratio
CI: confidence interval
*: adjusted for age, sex, social class, parental allergic disease and number of brothers
#: adjusted for age, sex, social class, parental allergic disease and relevant infection count