Table 2—

Size and distribution of fibre types in the diaphragm and quadriceps femoris#

Control diaphragmCOPD group
DiaphragmVastus lateralis
CSA‐I µm23015±1983534±3583610±459
CSA‐II µm23421±2693994±3693837±719
MyHC‐I %68.8±4.070.2±3.026.4±3.7***
MyHC‐II %35.6±6.429.8±3.074.5±3.7***
  • Data are presented as mean±sem

  • COPD: chronic obstructive pulmonary disease

  • MyHC‐I and ‐II: myosin heavy chain type I and type II

  • CSA‐I and ‐II: cross-sectional area of MyHC‐I and ‐II fibres, respectively

  • #: vastus lateralis

  • ***: p<0.001 versus COPD group diaphragm