Patient characteristics
| First HRCT | Second HRCT | Mean annual change | |
| Age yrs | 11.05±3.30 | 13.04±3.30 | Interval 1.99 |
| Body height m | 1.37±0.21 | 1.47±0.20 | 0.047* |
| Body weight kg | 32.5±12.1 | 38.6±13.9 | 3.46* |
| FEV1 % pred | 74.3±18.2 | 76.0±21.0 | 1.24 |
| FVC % pred | 85.5±15.7 | 85.1±16.2 | −0.11 |
| FEF25–75% pred | 58.8±31.2 | 59.9±32.0 | −1.30 |
| FEV1/FVC % | 75.4±10.6 | 77.6±9.8 | 0.39 |
| Raw % pred | 136.1±61.8 | 143.4±76.0 | 0.10 |
| RV % pred | 136.6±42.1 | 129.9±40.2 | −8.49* |
| TLC % pred | 98.0±13.2 | 96.8±11.2 | −1.06 |
| RV/TLC % | 33.2±9.4 | 31.6±9.7 | −2.11* |
| Castile score 2 | 17.7±9.7 | 22.4±11.4 | 2.39* |
| Brody score 3 | 12.1±8.7 | 16.3±10.2 | 2.21* |
| Helbich score 4 | 8.4±3.7 | 10.1±3.8 | 0.88* |
| Santamaria score 5 | 8.9±4.0 | 10.7±4.1 | 0.91* |
| Bhalla score 6 | 8.2±3.4 | 10.0±3.6 | 0.87* |
Data are presented as mean±sd
HRCT: high-resolution computed tomography
FEV1: forced expiratory volume in one second
% pred: % predicted
FVC: forced vital capacity
FEF25–75%: forced mid-expiratory flow
Raw: airway resistance
RV: residual volume
TLC: total lung capacity
*: p<0.05 in 1 yr with the one-sample t–test (unpaired)