Table 4

Examples of the estimation of cumulative (overall) multivariate likelihood ratios (LR) for the prediction of “asthma symptoms” in adulthood, based on various combinations of characteristics in childhood

Atopy		AHR		Recent wheeze		Obstructive spirometry		Female		Cumulative multivariate LR
Present	LR	Present	LR	Present	LR	Present	LR	Present	LR	Cumulative multivariate LR
Yes	2.02	Yes	2.56	Yes	1.92	Yes	2.88	Yes	1.29	36.9
Yes	2.02	Yes	2.56	Yes	1.92	Yes	2.88	No	0.77	22.0
Yes	2.02	Yes	2.56	Yes	1.92	No	0.96	Yes	1.29	12.3
Yes	2.02	Yes	2.56	No	0.92	No	0.96	No	0.77	3.5
No	0.79	Yes	2.56	Yes	1.92	No	0.96	Yes	1.29	4.8
Yes	2.02	No	0.89	No	0.92	No	0.96	No	0.77	1.2
No	0.79	No	0.89	No	0.92	No	0.96	Yes	1.29	0.80
No	0.79	No	0.89	No	0.92	No	0.96	No	0.77	0.48

AHR: airway hyperresponsiveness