Clinical details of study population
| Stillborn foetuses | Preterm infants# | ||||||
| Total | Duration of ventilation days | Surfactant treatment | |||||
| 0–1 | 1–3 | >3 | Yes | No | |||
| Subjects n | 29 | 27 | 15 | 5 | 7 | 16 | 11 |
| Gestational age weeks | 28.0±0.8 | 27.9±0.7 | 27.5±0.9 | 26.2±1.3 | 30.1±1.4 | 27.0±0.9 | 28.6±1.0 |
| Birthweight g | 1006±114 | 1138±106 | 1064±117 | 876±247 | 1614±220 | 1007±172 | 1285±135 |
| Length cm | 34.8±1.5 | 38.0±1.1 | 37.6±1.4 | 35.6±3.0 | 41.4±1.0 | 38.0±1.6 | 38.4±1.4 |
| Mean Paw mmHg | – | 21.9±1.9 | 23.8±2.8 | 19.9±3.4 | 19.3±3.0 | 18.8±2.2 | 24.1±2.6 |
| Mean FI,O2 | – | 0.7±0.1 | 0.9±0.1 | 0.6±0.1 | 0.5±0.1 | 0.7±0.1 | 0.8±0.1 |
| Males/females n | 11/18 | 16/11 | 8/7 | 4/1 | 4/3 | 10/6 | 6/5 |
Data are presented as mean±sem
The median duration of ventilation of children ventilated for >3 days was 6.8 days
Paw: airway pressure during artificial ventilation
FI,O2: inspiratory oxygen fraction during artificial ventilation
Stillborn foetuses died because of abortion (n=18), intrauterine foetal death (n=2), ablatio placentae (n=4), intrauterine asphyxia (n=4) and circulatory failure (n=1)
Causes of death of ventilated preterm infants with respiratory distress syndrome (RDS) were respiratory insufficiency (n=14), circulatory failure (n=11) and cerebral haemorrhage (n=2)
#: ventilated/oxygen-treated due to RDS
(1 mmHg=0.133 kPa)