Childhood characteristic | Asthma Symptoms (n=200) | Troublesome Asthma ( n=82) | ||||||
Unadjusted OR | p‐value | Adjusted OR | p‐value | Unadjusted OR | p‐value | Adjusted OR | p‐value | |
Atopy | 3.2 (2.1–4.9) | <0.001 | 2.6 (1.6–4.0) | <0.001 | 4.0 (2.5–6.6) | <0.001 | 4.0 (2.3–7.2) | 0.0001 |
AHR | 5.1 (2.8–9.4) | <0.001 | 2.9 (1.5–5.6) | 0.002 | 3.7 (2.0–6.8) | <0.001 | ||
Recent wheeze | 4.1 (2.3–7.2) | <0.001 | 2.1 (1.1–5.0) | 0.02 | 4.0 (2.2–7.2) | <0.001 | ||
FEV1/FVC ratio <80% | 3.4 (1.3–8.6) | 0.02 | 3.0 (1.0–9.1) | 0.05 | 3.7 (1.4–9.8) | 0.008 | 4.1 (1.4–12.3) | 0.02 |
Female | 1.3 (0.9–1.8) | 0.2 | 1.7 (1.1–2.4) | 0.008 | 1.9 (1.1–3.0) | 0.01 | 3.2 (1.8–5.7) | 0.0001 |
Diagnosed asthma | 2.6 (1.5–4.6) | 0.001 | 2.1 (1.1–4.0) | 0.03 | ||||
Eczema | 1.6 (1.1–2.4) | 0.03 | 2.2 (1.3–3.6) | 0.003 | ||||
Hayfever | 2.6 (1.7–3.9) | <0.001 | 4.1 (2.5–6.8) | <0.001 | 2.9 (1.7–5.1) | 0.0002 | ||
Bronchitis before age 2 yrs | 1.9 (1.3–2.9) | 0.002 | 2.4 (1.4–3.9) | 0.002 | ||||
Maternal asthma | 1.2 (0.7–2.1) | 0.5 | 1.1 (0.5–2.4) | 0.8 | ||||
Maternal allergies | 1.1 (0.8–1.6) | 0.5 | 1.5 (0.9–2.3) | 0.1 | ||||
Paternal asthma | 1.6 (0.8–2.9) | 0.2 | 2.4 (1.2–4.8) | 0.02 | ||||
Paternal allergies | 1.0 (0.7–1.4) | 0.9 | 1.2 (0.7–2.0) | 0.4 |
Data are presented as OR (95% confidence interval) unless otherwise stated
AHR: airway hyperresponsiveness
FEV1: forced expiratory volume inone second
FVC: forced vital capacity
Variables were included in the final model if p<0.05
The variables in the final model were adjusted for eachother