Tiotropium | Ipratropium | Difference | 95% CI | |
Patients n | 344 | 175 | ||
Hospital admissions | 0.13 (0.02) | 0.24 (0.05) | −0.11 | −0.21–−0.01 |
Inpatient days in | ||||
General ward | 1.62 (0.33) | 2.96 (0.58) | −1.34 | −2.64–−0.004 |
ICU | 0.10 (0.09) | 0.02 (0.02) | 0.08 | −0.10–0.26 |
Total | 1.72 (0.37) | 2.98 (0.58) | −1.26 | −2.60–0.09 |
Unscheduled visits | ||||
Pulmonologist | 0.58 (0.06) | 0.68 (0.10) | −0.10 | −0.33–0.13 |
GP | 1.16 (0.10) | 1.48 (0.19) | −0.32 | −0.75–0.11 |
Other HCP | 0.25 (0.08) | 0.88 (0.39) | −0.63 | −1.42–1.52 |
Emergency room | 0.05 (0.01) | 0.14 (0.03) | −0.09 | −0.16–−0.02 |
Total | 2.04 (0.16) | 3.18 (0.52) | −1.14 | −2.20–−0.08 |
Ambulance transports | 0.05 (0.02) | 0.16 (0.07) | −0.11 | −0.25–0.02 |
Puffs of salbutamol (rescue medication) | 605 (42) | 714 (68) | −109 | −267–47 |
Inactivity days* | 23.98 (2.87) | 29.19 (4.03) | − 5.21 | −14.92–4.49 |
All data presented as mean (sem) unless otherwise stated
CI: confidence intervals
ICU: intensive care unit
GP: general practitioner
HCP: healthcare provider
*: Description in the case report form was “number of days unable to perform the majority of usual daily activities”