Table 1

Subject characteristics

HealthyCoughersWheezers
Subjects n231631
M/F12/1110/624/7
Age weeks40.1 (21.2)54.9 (23.3)52.9 (24.3)
Height cm71.7 (5.7)75.7 (6.4)75.0 (6.3)
Weight kg8.9 (1.6)#10.2 (1.4)10.3 (2.0)
FEV0.5 mL·s−1179.2 (42.6)186.9 (49.9)173.7 (36.9)
SB FENO ppb23.2 (18.3–29.4)+27.9 (21.1–37.1)32.9 (26.1–41.6)
TB FENO ppb13.8 (10.4–18.3)12.6 (8.0–20.0)15.6 (13.1–18.5)
  • Data are presented as mean (sd) or geometric mean (95% confidence interval) unless otherwise stated

  • M: male

  • F: female

  • FEV0.5: forced expiratory volume in 0.5 seconds

  • SB FENO: single breath fractional exhaled nitric oxide

  • TB FENO: tidal breathing exhaled nitric oxide

  • #: significantly lower than both wheezy and coughing groups (p=0.02)

  • : significantly lower than healthy group after controlling for age (p=0.01)

  • +: significantly lower than wheezy group (p=0.01)