Comparison of lung function tests results from children with cystic fibrosis (CF) and the healthy controls
| CF | Controls | CF‐controls | |
| Patients n | 43 | 28 | |
| FEV1 % pred | 89.1 (19.8) | 96.9 (10.3) | −15.9–0.3# |
| MEF50 % pred¶ | 92.3 (41.2) | 107.0 (30.2) | −33.9–4.6 |
| MEF25 % pred¶ | 64.5 (33.5) | 86.5 (28.2) | −38.3–−5.7** |
| RV/TLC+ | 26.5 (10.6) | 22.8 (4.3) | −0.7–8.1 |
| MR | 1.61 (0.49) | 1.19 (0.08) | 0.23–0.61*** |
| LCI | 8.33 (2.48) | 6.33 (0.43) | 1.06–2.95*** |
Data are presented as mean (SD) and 95% confidence interval for the difference between the groups unless otherwise stated
FEV1: forced expiratory volume in one second
% pred: % predicted
MEF50: maximum expiratory flow at 50% of forced vital capacity
MEF25: maximum expiratory flow at 25% of forced vital capacity
RV: residual volume
TLC: total lung capacity
MR: mixing ratio
LCI: lung clearance index
#: p=0.06
¶: MEF50 and MEF25 results were available for analyses in 34 CF patients and 26 controls
+: RV/TLC results were available for analyses in 35 CF patients and 27 controls
**: p<0.01
***: p<0.001