Table 1

Patient characteristics in two asthmatic groups

Group AGroup B
Subjects n1014
Age yrs48±561±4
F/M n5/57/7
Length of illness yrs8.9±2.913.1±2.1
Atopic/nonatopic n7/39/5
Peripheral eosinophils µL334±112355±85
Serum IgE# IU1148±801642±322
VC % pred120.5±3.594.9±5.4**
FEV1 % pred before BD96.0±3.862.9±1.8**
FEV1/FVC % before BD76.5±2.063.2±2.2**
FEV1 % pred after BD102.4±3.769.8±2.3**
FEV1/FVC % after BD79.4±2.164.0±1.8**
RV/TLC %41.7±2.752.4±2.6*
DL,CO % pred111.3±7.7103.1±3.3
  • Data are presented as mean±sem unless otherwise stated

  • F: female

  • M: male

  • Ig: immunoglobulin

  • VC: vital capacity

  • % pred: % predicted

  • FEV1: forced expiratory volume in one second

  • BD: bronchodilator

  • FVC: forced vital capacity

  • RV: residual volume

  • TLC: total lung capacity

  • DL,CO: diffusing capacity of the lung for carbon monoxide

  • #: normal range <400 IU·mL−1

  • Group A patients had normal FEV1 and FEV1/FVC after BD inhalation

  • In group B patients, FEV1 or FEV1/FVC remained abnormal after BD inhalation

  • *: p<0.05 versus group A

  • **: p<0.01 versus group A