Table 2

Comparison of lung function results in infants with and without cystic fibrosis

Cystic fibrosis infantsHealthy infantsCystic fibrosis-healthy infants#
Subjects n4795
Respiratory rate min−142.9 (10.5)35.2 (7.3)7.7 (4.3–11.1)*,***
VT mL68.5 (21.2)72.2 (21.5)−3.7 (−3.8–11.3)
VT mL·kg−110.1 (1.6)9.0 (1.3)1.1 (0.5–1.6)***
MV mL·kg−1424 (94.3)313 (59.6)111 (81–141)***
TPTEF:TE0.266 (0.085)0.263 (0.073)0.003 (−0.024–0.031)
FEV0.4 mL159.6 (58.0)226.0 (69.2)−66.3 (−90.4–−42.1)***
FEV0.4 SD score−0.95 (0.83)0.01 (0.99)−0.96 (−1.3–−0.61)***
  • Data are presented as mean (sd) unless otherwise stated

  • VT: tidal volume

  • MV: minute ventilation

  • TPTEF:TE: tidal breathing ratio

  • FEV0.4: forced expiratory volume in 0.4 seconds

  • #: difference (95% confidence interval)

  • : n=42

  • *: p<0.05

  • ***: p<0.001