Absolute values for ventilatory variables at rest and exercise during normoxia and hypoxia
| II | ID | DD | p‐value | ||
| F:M | 14:8 | 30:18 | 16:10 | ||
| Resting V'E L·min−1 | Normoxic | 11.92±0.60 | 11.15±0.50 | 11.42±0.50 | |
| Hypoxic | 15.52±1.90 | 13.84±0.60 | 13.28±0.59 | ||
| Change | 3.6±1.5 | 2.7±0.5 | 1.87±0.4 | ||
| Change % | 27.0±9.2 | 26.5±4.3 | 17.4±3.8 | 0.3 | |
| Exercise V'E L·min−1 | Normoxic | 33.87±2.3 | 35.53±1.2 | 36.06±1.40 | |
| Hypoxic | 47.35±3.6 | 45.40±1.7 | 46.57±2.40 | ||
| Change | 13.48±1.7 | 9.87±0.8 | 10.51±1.10 | ||
| Change % | 39.6±4.1 | 27.9±2.0 | 28.4±2.2 | 0.02 | |
| Resting VT L | Normoxic | 0.90±0.10 | 0.79±0.05 | 0.87±0.07 | |
| Hypoxic | 1.07±0.20 | 0.95±0.05 | 1.00±0.08 | ||
| Change | 0.17±0.10 | 0.15±0.30 | 0.14±0.06 | ||
| Change % | 15.8±3.2 | 23.0±3.8 | 18.2±6.4 | 0.8 | |
| Exercise VT L | Normoxic | 1.77±0.10 | 1.78±0.09 | 1.80±0.10 | |
| Hypoxic | 2.04±0.20 | 2.01±0.10 | 2.03±0.10 | ||
| Change | 0.27±0.07 | 0.23±0.04 | 0.24±0.04 | ||
| Change % | 15.0±3.1 | 12.9±2.1 | 13.7±2.4 | 0.7 | |
| Resting RR breaths·min−1 | Normoxic | 14.75±0.9 | 15.26±0.60 | 14.79±0.80 | |
| Hypoxic | 16.05±0.8 | 15.77±0.60 | 14.54±1.00 | ||
| Change | 1.29±0.9 | 0.5±0.6 | −0.25±0.50 | ||
| Change % | 11.0±5.7 | 4.8±3.7 | −1.7±3.6 | 0.06 | |
| Exercise RR breaths·min−1 | Normoxic | 19.84±0.80 | 21.14±0.80 | 21.52±1.20 | |
| Hypoxic | 23.74±1.00 | 23.89±0.90 | 24.10±1.30 | ||
| Change | 3.89±0.90 | 2.74±0.50 | 2.57±0.50 | ||
| Change % | 20.9±5.6 | 13.6±2.7 | 12.6±2.4 | 0.2 |
Data are presented as mean±sem unless otherwise stated.
F: female
M: male
V'E: minute ventilation
VT: tidal volume
RR: respiratory rate.
Absolute changes and percentage changes for each genotype group (insertion homozygote (II), heterozygote (ID), deletion homozygote (DD)).
p‐values are for analysis of variance comparisons made on percentage changes between homozygote groups