Table 2

Patient details, lung function, quality of life and atopic status in asthmatics

Confirmed asthmaUnconfirmed asthma
Subjects n5520
Age yrs36±12.547.7±15.2
Sex M:F14:419:11
Age at onset yrs
 <203812
 >20178
Ventilated113
Smokers82
FEV1 %63.6±23.966.4±22.8
FVC %86.6±1789.6±20.2
TLC %107.2±16.4105.3±17.9
TL,CO %90.5±19.391.9±21.6
sGaw %61.8±57.558.9±26.6
PEF %63.3±17.370.9±22.4
Amplitude mean %27.3±18.410.9±4.0
Blood gases
 H+34.5±5.5134±3.8
Pa,CO24.52±0.614.43±0.9
Pa,O210.89±2.5810.82±2.9
 HCO323.04±2.4523.2±2.9
SGRQ scores
 Total61.8±17.358.1±21.9
 Symptoms82.7±12.575.8±12.8
 Activities68.8±25.368.8±28.6
 Impact51.6±20.148.2±22.0
 GHQ 30 questionnaire2.5 (0–27, 17≥5)5.5 (0–25, 9≥5)
Atopy
 Atopic3911
 Total IgE
  Atopics145 (20–8300)314 (10–2620)
  Nonatopics47 (2–252)24 (7–112)
 House dust mite sensitised30±388±10
 Grass pollen sensitised21±3310±10
 Cat sensitised18±194±2
 Dog sensitised13±142±2
 Aspergillus IgE74
  • Data are presented as mean±sd, except age at onset, whether ventilated and smoking status (numbers in each category).

  • Lung function is shown as per cent predicted values (using European Respiratory Society predicted tables for height and age) and amplitude mean per cent peak expiratory flow (PEF) over a 14‐day period was calculated as described in 16

  • St George's Respiratory Questionnaire (SGRQ) scores are percentages (with high scores indicating impaired quality of life) and General Health Questionnaire (GHQ 30) is an arbitrary score for which a score of ≥5 is indicative of “psychiatric caseness”

  • M: male

  • F: female

  • FEV1: forced expiratory volume in one second

  • FVC: forced vital capacity

  • TLC: total lung capacity

  • TL,CO: transfer coefficient of the lung for carbon monoxide

  • sGaw: specific airway conductance

  • Pa,CO2: arterial carbon dioxide tension

  • Pa,O2: arterial oxygen tension

  • IgE: immunoglobulin E