Effect of cyclosporin A on the percentages of different cell types in bronchoalveolar lavage fluid before and after allergen inhalation challenge
| Placebo | Cyclosporin A | Between-group p‐value | |||||
| Baseline | Allergen | p‐value | Baseline | Allergen | p‐value | ||
| Neutrophils % | 1.5 (0.6–4.5) | 5.1 (0.9–10.9) | 0.029 | 3.7 (0.0–8.7) | 6.7 (1.2–21.9) | ns | ns |
| Eosinophils % | 1.3 (0.3–12.3) | 5.4 (1.6–13.0) | 0.004 | 8.8 (0.9–34.1) | 13.4 (3.0–35.5) | ns | ns |
| Total T‐cells % | 5.4 (2.4–9.1) | 6.5 (2.8–8.3) | ns | 6.7 (2.9–10.5) | 6.2 (2.4–8.9) | ns | ns |
| Macrophages % | 85.8 (81.2–93.8) | 82.1 (74.6–84.4) | 0.004 | 82.8 (60.0–89.8) | 69.1 (37.8–81.4) | 0.025 | ns |
| Epithelial cells % | 3.0 (2.0–6.3) | 3.8 (1.6–7.1) | ns | 3.3 (1.2–5.2) | 3.0 (1.8–4.0) | ns | ns |
Data are presented as median (range).
ns: nonsignificant