Table 3

Comparison of haem oxygenase (HO)-2-, inducible nitric oxide synthase (iNOS)- and nitrotyrosine (NTyr)-positive cells in the alveolar wall in the two groups of subjects

Severe COPDControl smokers
HO-2+ cells·mm−1 of alveolar wall18.0* (12.7–22.8)11.3 (10.6–12.2)
iNOS+ cells·mm−1 of alveolar wall13.9** (11.4–19.2)4.2 (2.3–5.9)
N-Tyr+ cells·mm−1 of alveolar wall26.4 (11.2–42.2)8.5 (4.6–21.0)
  • Values are expressed as medians (interquartile range)

  • COPD: chronic obstructive pulmonary disease

  • *: p<0.01

  • **: p<0.001 versus control smokers