Table 2

Comparison of alveolar macrophages per high-power field (hpf) and percentages of haem oxygenase (HO)-1-, inducible nitric oxide synthase (iNOS)- and nitro-tyrosine (N-Tyr)-positive alveolar macrophages in the two groups of subjects

Severe COPDControl smokers
Macrophages·hpf−1 n4.4 (3.1–4.9)4.2 (3.1–5.8)
HO-1+ macrophages %26.0* (12.3–32.6)44.1 (34.7–57.5)
iNOS+ macrophages %52.1 (28.1–75.3)50.9 (41.4–53.8)
N-Tyr+ macrophages %66.2 (34.7–78.1)65.0 (46.9–78.7)
  • Values are expressed as medians (interquartile range)

  • COPD: chronic obstructive pulmonary disease

  • *: p<0.01 versus control smokers