Table 1—

Physiological characteristics of study subjects

COPD patientsNormal subjects
Subjects n148
Age yrs74.6±5.760.4±13.5
FEV1 L1.20±0.362.66±1.27
FEV1 % pred51.1±15.889.6±17.7
FVC L2.70±0.753.72±1.66
FEV1/FVC47.4±13.478.4±7.5
Pa,O2 kPa8.80±1.829.96±0.72
Pa,CO2 kPa5.20±0.575.32±0.66
Pack-yrs of smoking51.5±24.049.0±44.0
MRC dyspnoea score3.20±1.331.00±0.00
Current smokers86
  • Data are presented as mean±sd unless otherwise stated

  • COPD: chronic obstructive pulmonary disease

  • FEV1: forced expiratory volume in one second

  • % pred: % predicted

  • FVC: forced vital capacity

  • Pa,O2: arterial oxygen tension

  • Pa,CO2: arterial carbon dioxide tension

  • MRC: Medical Research Council