Table 2

Immunohistochemical assessment of interleukin (IL)‐13+ and ‐4+ cells in the bronchial epithelium and glands of smokers and nonsmokers

Subjects nIL‐13+ cellsIL‐4+ cells
Bronchial epithelium cells·mm−1Bronchial glands cells·mm−2Bronchial epithelium cells·mm−1Bronchial glands cells·mm−2
CB210.3 (0.1–0.7)5.0 (2.3–8.1)1.5 (0.9–2.9)20.9 (11.3–26.1)
AS100.2 (0.0–0.8)1.4 (0.0–4.9)1.0 (0.6–1.6)13.3 (5.6–30.4)
NS20.4 (0.1–0.8)1.5 (0.0–3.0)0.3 (0.0–0.7)1.2 (1.0–1.4)
  • Data are expressed as median (25th–75th percentile)

  • CB: smokers with symptoms of chronic bronchitis

  • AS: asymptomatic smokers; NS: nonsmokers

  • Epithelium: IL‐4, CB, number of observations=20

  • IL‐13, AS, number of observations=9

  • Glands: IL‐13, AS, number of observations=9

  • No significant differences were observed between the groups