Table 1—

Pulmonary function and daytime blood gases (breathing air) prior to treatment (baseline) and when on treatment during at least 6 months (end)

LTO group#nNIPPV groupDifference between LTO and nNIPPV group p‐values
BaselineEndħBaselineEndħBaselineEndħ
nmean±sdnmean±sdnmean±sdnmean±sdnmean±sdnmean±sd
Age yrs1562±71861±7ns
Height cm15153±1418145±11ns
FEV1/VC1578±181882±12ns
PO2 on air mmHg1550±711+56±911+13±131844±81866±101854±34<0.050.010.001
PCO2 on air mmHg1555±711+52±511+0±61860±81847±818−21±11NS0.010.0001
VC % pred1540±169+46±169+6±231832±121844±101847±44NSNS<0.01
VC mL15970±3879+1064±4529+4±2418645±24418830±2921851±53<0.01NS<0.01
MIP % predNA1244±131257±171233±30
MIP kPaNA123.7±1.1124.8±1.21234±31
  • LTO: long-term oxygen therapy at home

  • nNIPPV: nocturnal nasal intermittent positive pressure ventilation at home

  • FEV1: forced expiratory volume in one second

  • VC: vital capacity

  • PO2: partial pressure of oxygen

  • PCO2: partial pressure of carbon dioxide

  • MIP: maximal inspiratory muscle force

  • NA: not available

  • ns: nonsignificant

  • #: LTO group (10 males and five females)

  • : nNIPPV group (14 males and four females)

  • +: four patients died before re-evaluation was possible and in two remaining patients a spirometric measurement was not possible

  • §: (value before treatment–value after start of treatment)/value before treatment

  • Conversion factor mmHg to kPa×0.133