Levels of significance of the differences between the parameters under consideration and different inhalation devices calculated using a paired t‐test
| p‐values | |||
| Dt | Dp | T50 | |
| HaloLite® versus LC Star® | 0.82 | 0.94 | 0.001 |
| HaloLite® versus AKITA® | 0.041 | 0.001 | 0.002 |
| Sidestream® | |||
| HaloLite® versus AKITA® | 0.042 | <0.001 | 0.003 |
| LC Star® | |||
| LC Star® versus AKITA® | 0.007 | 0.01 | 0.034 |
| Sidestream® | |||
| LC Star® versus AKITA® | 0.005 | 0.008 | 0.031 |
| LC Star® | |||
| AKITA® Sidestream® versus | 0.074 | 0.031 | 0.036 |
| AKITA® LC Star® | |||
Dt: total deposition
Dp: peripheral deposition
T50: time required to inhale 50 mg of α1‐protease inhibitor