Cytokine messenger ribonucleic acids (mRNAs) expressed in similar amounts in lung tissue from patients with idiopathic pulmonary fibrosis (IPF) and control subjects
| Cytokine | Expression of cytokine mRNAs | |
| IPF | Controls | |
| PDGF‐A | 143±107 | 193±62 |
| PDGF‐B | 2094±1619 | 2408±1331 |
| aFGF | 252±340 | 202±155 |
| bFGF | 1650±2001 | 1011±904 |
| KGF# | 1820±3361 | 292±279 |
| TGF‐α# | 1704±2706 | 496±131 |
| IGF‐2 | 101±90 | 107±54 |
| EGF | 139±110 | 97±45 |
| IL‐1β | 99±90 | 230±147 |
| IL‐6 | 291±446 | 435±807 |
| IL‐8 | 898±1602 | 2890±1327 |
| IL-15 | 666±515 | 812±436 |
| GM-CSF | 168±133 | 282±303 |
| IFN‐γ | 235±185 | 190±55 |
| TNF‐α | 457±279 | 709±120 |
Results of dot blots for the indicated cytokines are shown for control subjects (n=5) and patients with IPF (n=5), presented as counts per minute±sd
PDGF: platelet-derived growth factor
FGF: fibroblast growth factor
KGF: keratinocyte growth factor
TGF: transforming growth factor
IGF: insulin growth factor
EGF: epithelial growth factor
IL: interleukin
GM-CSF: granulocyte-macrophage colony-stimulating factor
IFN: interferon
TNF: tumour necrosis factor
#: a single sample expressed increased amounts of mRNA coding for these cytokines