Table 2

Forced expiratory volume in one second (FEV1) at rest and after β2-agonist therapy, and the maximum relative fall in FEV1 after cold dry-air hyperventilation challenge (CACh) in the three subgroups

ABCp-values
A vs BA vs CB vs C
Subjects n271612
Resting FEV1 % pred95.3 ±12.589.6±7.588.2±11.3nsnsns
Max. fall in FEV1 %4.7±2.814.2±3.137.6±8.9<0.001<0.001<0.001
Post-β2 FEV1 % pred99.1±12.892.8±6.390.7±12.2nsnsns
  • Data are presented as mean±sd

  • A: nonresponders

  • B: minor responders

  • C: major responders

  • vs: versus

  • % pred: % predicted

  • max.: maximum

  • ns: nonsignificant