Baseline lung function (visit 1) and salbutamol dose/response in the methacholine- challenge test at screening (visits 1 and 2)
| Randomised | Completed | |
| Patients n | 26 | 18 |
| FEV1 | ||
| L | 3.0±0.8 (2.0–4.9) | 3.0±0.7 (2.1–4.7) |
| % predicted | 86±11 (72–110) | 88±11 (74–110) |
| Methacholine challenge | ||
| Baseline PC20 mg·mL−1 | 1.0±0.9 (0.1–3.0) | 0.8±0.8 (0.1–3.0) |
| Salbutamol dose/response | ||
| PC20 post 100 µg | 4.7±5.1 (0.2–18.9) | 4.0±3.3 (0.8–11.9) |
| PC20 post 200 µg | 13.3±18.1 (0.9–93.9) | 10.4±7.3 (1.8–27.0) |
| Ratio PC20 post 200:100 µg | 3.9±3.3 (1.1–12.5) | 3.4±2.8 (1.1–12.5) |
Data are presented as mean±sd (range), unless otherwise stated
FEV1: forced expiratory volume in one second
PC20: provocative concentration of methacholine causing a 20% fall in FEV1