Table 1

Asthma patient baseline characteristics by treatment group

PlaceboSalmeterolFluticasone
Subjects n161316
Males/females n7/98/511/5
Age yrs33 (22–68)38 (20–70)42 (22–63)
ICS dose µg·day−1400 (200–500)400 (200–500)400 (200–500)
Atopic/nonatopic n12/413/011/5
PD20 mg0.011 (0.001–0.16)0.022 (0.01–0.56)0.021 (0.003–0.46)
FEV1 % pred83 (61–109)84 (63–106)80 (61–102)
24-h symptom score1.07 (0.57–4.21)1.21 (0.01–3.29)1.39 (0.57–2.57)
24-h salbutamol use puffs·day−11.07 (0.57–5.50)1.21 (0.57–4.86)1.82 (0.50–5.36)
  • Data are presented as median (range), and as geometric mean (range) for provocative dose of methacholine causing a 20% fall in forced expiratory volume in one second (FEV1) (PD20)

  • Full clinical details are presented in 14

  • ICS: inhaled corticosteroid

  • % pred: percentage of the predicted value