Table 1

Patient characteristics at baseline

CharacteristicsModerate‐to‐severe FEV1 <50% predMild FEV1 ≥50% pred
Subjects n195196179180
Age yrs64±764±663±863±8
Male %81866663
Smoking history
 Current smokers %38324141
 Exsmokers %48514443
 Intermittent %14171616
Atopy# %14131114
FEV1 L1.0±0.21.0±0.31.6±0.51.6±0.5
FEV1% pred39±839±862±1062±10
% FEV1 reversibility+4.1±3.44.2±3.44.8±3.44.6±3.6
  • Data are presented as mean±sd

  • FEV1: forced expiratory volume in one second

  • FP: fluticasone propionate

  • % pred: % predicted

  • #: atopy defined as positive skin-prick test to one or more common allergens

  • : prebronchodilator FEV1

  • +: change in FEV1 after bronchodilator expressed as % pred. There were no significant differences (p>0.05) between the treatment groups, within each severity category, for any variable. Except for proportionally more females in the mild compared to the moderate‐to‐severe group (p<0.001) and more pack-yrs smoked in the moderate-severe group