Males | Females | |||||
20–39 yrs | 40–59 yrs | 60–80 yrs | 20–39 yrs | 40–59 yrs | 60–80 yrs | |
Anthropometric | ||||||
Height cm | 171.2±5.3** | 166.5±6.7 | 167.4±6.2 | 160.3±6.7**,## | 156.9±5.8## | 155.2±6.2## |
Weight kg | 72.8±10.7 | 77.0±15.2 | 73.7±8.5 | 63.9±13.8## | 63.4±10.7## | 62.8±8.5## |
BMI kg·m−2 | 25.2±3.3 | 27.1±5.2 | 25.9±3.1 | 27.5±8.2 | 26.3±3.6 | 26.0±3.5 |
Resting functional | ||||||
FVC % pred | 93.3±10.5 | 104.5±8.7 | 96.3±7.9 | 90.5±8.1 | 98.5±10.1 | 101.7±12.9 |
FEV1 % pred | 89.7±7.5 | 93.1±5.9 | 90.5±8.1 | 92.5±10.3 | 87.9±5.7 | 98.1±12.0 |
FEV1/FVC | 0.80±0.06 | 0.77±0.04 | 0.75±0.05 | 0.83±0.04 | 0.78±0.04 | 0.75±0.04 |
TLC % pred | 108.3±14.2 | 95.2±12.5 | 102.9±11.9 | 90.8±18.1 | 110.1±10.3 | 105.3±15.8 |
DL,CO % pred | 98.3±18.6 | 105.2±15.5 | 89.9±12.9 | 100.8±20.1 | 111.1±21.8 | 106.4±17.8 |
MIP cmH2O | 133.3±19.4** | 117.4±25.5 | 92.5±24.3 | 93.6±11.4** | 84.4±9.1## | 75.7±4.8## |
MVV L·min−1 | 168.5±25.6** | 140.4±30.3 | 120.7±23.2 | 124.2±12.1**,## | 110.9±14.3## | 94.6±18.6## |
Peak exercise | ||||||
Work-rate W | 185±32** | 143±30 | 105±19 | 116±19**,## | 93±17## | 61±15## |
V′O2 mL·min−1 | 2621±366** | 2085±345 | 1585±210 | 1679±228**,## | 1319±143## | 1052±116## |
RER | 1.21±0.08 | 1.18±0.06 | 1.17±0.10 | 1.16±0.08 | 1.15±0.09 | 1.12±0.10 |
fC beats·min−1 | 187±10** | 169±11 | 149±17 | 182±12** | 174±11 | 148±17 |
% pred | 99.3±3.1 | 95.0±3.5 | 101.3±3.5 | 97.7±3.5 | 101.1±3.4 | 102.5±2.2 |
V′E,max L·min−1 | 119.6±28.3** | 98.7±22.2 | 76.7±11.7 | 75.8±13.7**,## | 67.3±11.2## | 50.1±10.0## |
V′E,max/MVV | 0.69±0.12 | 0.69±0.11 | 0.67±0.13 | 0.60±0.11## | 0.60±0.11## | 0.56±0.12## |
Data are presented as mean±sd (n=20 for each group)
BMI: body mass index
FVC: forced vital capacity
FEV1: forced expiratory volume in one second
TLC: total lung capacity
DL,CO: lung diffusion capacity for carbon monoxide
MIP: maximal inspiratory pressure
MVV: maximal voluntary ventilation
V′O2: oxygen uptake
RER: respiratory exchange ratio
fC: cardiac frequency
V′E,max: maximal minute ventilation
% pred: percentage of the predicted value
**: p<0.01 versus other age groups within sex
##: p<0.01 versus males