Table 3—

Summary of the stepwise logistic regression analysis for the effects of initial provocative dose causing a 20% fall in the forced expiratory volume in one second (PD20), duration of exposure, duration of follow-up and treatment with inhaled steroids among subjects with PD20 ≤1 mg and >1 mg at follow-up#

VariableModel 0Model 1Model 2Model 3
Initial PD20, log dose
 B−2.422−2.313−3.42−2.14
 se1.0391.0491.3841.070
 OR0.080.090.030.11
 CI0.01–0.680.01–0.770.002–0.490.01–0.95
 p-value0.020.020.010.04
Duration of exposure, yrs
 B−0.08−0.08−0.13−0.10
 se0.0600.0610.0710.074
 OR0.910.920.870.90
 CI0.81–1.030.81–1.040.76–1.010.78–1.04
 p-value0.160.190.060.16
Last exposure to TDI yrsNINI
 B0.040.03
 se0.0890.102
 OR1.041.03
 CI0.87–1.240.84–1.26
 p-value0.110.72
Interval since removal from exposure yrs (≥10 <10)NI
 B2.02
 se1.172
 OR7.59
 CI0.76–75.6
 p-value0.08
Current inhaled steroids, yes versus no
 B2.22
 se1.211
 OR9.22
 CI0.85–99.08
 p-value0.06
Prediction82.982.987.282.9
  • #: dependent variable

  • PD20 ≤1 mg

  • Model: NI: variable not included in the model

  • 0: normal airway responsiveness (PD20 >1 mg)

  • 1: airway hyperresponsiveness (PD20 ≤1 mg)

  • 0: interval since removal from exposure ≥10 yrs

  • 1: interval since removal from exposure <10 yr

  • 0: no current inhaled steroids

  • 1: yes current inhaled steroids

  • B: regression coefficient

  • OR: odds ratio

  • CI: 95% confidence interval